Powder

Understanding pharmaceutical particle and powder characterization is key to efficient pharmaceutical manufacturing processes and products where they involve suspensions and bulk powders. Particle size and powder properties will influence bulk physical properties, such as the flowability of a powder, which in turn, will impact processing, blending, tableting, dissolution, delivery and bioavailability.

 

Powders may also be used to describe a type of pharmaceutical preparation, that is, a medicated powder intended for internal or external use.

 

Aipak offers various kinds of powder process machines include the sifter machine ,crusher machine,bin mixer,bin blender,dryer machine,granulation machine.With which you will be more easy to administer your drugs from hard vegetables such as roots,barks and woods.

 

The powder filling machine from Aipak will make you easy fill your various kinds of dry powder filling bottles, like protein powder ,pepper powder ,and other backing powder ,coffee powder organic powder ect. It is also suit for packing powder and small granular materials, such as veterinary medicine, granular additive, white granulated sugar, cotton,sugar, glucose, solid beverage, pharmaceutical solids, carbon powder, talcum powder, pesticides, dyes, flavors and fragrances.

Machines For Powder

Powder Filling Machines

Auger Filler Machine For powder

Auger Powder Filling Machine

Automatic Powder Filling Machine

Double Head Powder Filling Machine

Capsule Filling Machine

NJP-200C Capsule Filling Machine

NJP-400C Capsule Filling Machine

NJP-800C Capsule Filling Machine

NJP-1200C Capsule Filling Machine

NJP-1200D Capsule Filling Machine

NJP-2500C Capsule Filling Machine

NJP-3800C Capsule Filling Machine

NJP-5500C Capsule Filling Machine

NJP-7500C Capsule Filling Machine

CGN-208D Capsule Filling Machine

CGN208-D1 Capsule Filling Machine

CGN208-D2 Capsule Filling Machine

CGN208-D3 Capsule Filling Machine

CGN-208S Capsule Filling Machine

TM-100 200 250 Capsule Making Machine

RJN Capsule making machine

Bin Mixer

SWH Series 3D Motion Bin Mixer

GHS High speed Bin Mixer

Model CH-VI Forced-Type Bin Mixer

CH Series Tanker Typed Bin Mixer

Model EYH Series Bin Mixer

WSH Series Tank Type Bin Mixer

CH Series Typed Bin Mixer (2011)

WLDH- Horizontal Ribbon Bin Mixer

DLH Series Cone Bin Mixer

Model W Series Taper-shaped Bin Mixer

CW series stirring type Bin Mixer

Model CH-V Series Bin Mixer

Bin Blender

HDT Series Bin Blender

DTH Series Post Bin Blender

HGD Series Lab Bin Blender

Crusher Machine

GFSJ Series Crusher Machine

B Series Crusher Machine

WF Series Crusher Machine

YGJ Series Crusher Machine

DS Series Crusher Machine

WF Series Crusher Machine

Model B Series Crusher Machine

WCSJ Series Crusher Machine

WCSJ Series Dust Crusher Machine

WF Series Dust Crusher Machine

WCSJ Series Universal Crusher Machine

B Series Cyclone-separating Crusher Machine

CSJ Series Coarse Crusher

B Series Dust Collecting Crusher

GFSJ Series High Efficient Crusher

QS-100 Airflow Crusher

Model WF Series Crusher Machine

WFJ Series Dust Collecting Fine Crusher

YF Series Crusher Machine

WFM Series Super Crusher Machine

JCFJ Series Inner-Grading Mechanical Crusher

QLDJ Series Fluidized-bed Airflow Crusher

FYF Series Vegetables Crusher Machine

WFJ Series Dust Collecting Fine Crushing Set

JM Series Two-Stage Colloid Mill TAG

Granulation Machine

HLSG Series High Shear Mixer Granulator

Model YK-160 Swing High Shear Mixer Granulator

FL Series Mixer Granulator Drier

KZL Series High Speed High Shear Mixer Granulator

Model ZL Rotating High Shear Mixer Granulator

GK Series Dry High Shear Mixer Granulator

GHL Series High Speed High Shear Mixer Granulator

Dryer Machine

FG Series Fluid bed Dryer

LPG Series High-speed Pharmaceutical Dryer

DW Series Mesh-Belt Pharmaceutical Dryer

ZLG Series Vibration Fluidized Bed Dryer

SZG Series Double Cone Rotary Vacuum Dryer

GFG Efficient Boiling Pharmaceutical Dryer

FL300 Pharmaceutical Dryer

GF Series High Efficiency Fluidized Bed Drier

FZG,YZG squar and round static vacuum dryer

Model RXH Series Pharmaceutical Dryer

Sifter Machine

ZS Series Sifter Machine

LXS Series Sifter Machine

ZS Vibrating Sifter Machine

ZS Series Screening Machine

Videos For Powder

How Powder Crusher Machine Looks Like

How Crusher Machine Crushes Powder

How NJP-800 Automatic Capsule Filling Machine Fills Powder

How NJP-1200 Automatic Capsule Filling Machine Fills Powder

How Bin Blender Mixes Powder

How Powder Filling Machine Labels

How Semi Automatic Capsule Filling Machine Fills Powder

How NJP-200 Automatic Capsule Filling Machine Fills Powder

How NJP-800 Automatic Capsule Filling Machine Fills Powder

How Powder Filling Machine Fills Powder

Frequently Asked Questions

A pharmaceutical powder is defined as a dry, solid substance, composed of finely divided drugs with or without excipients and intended for internal or external use. It is a solid substance in finely divided state typically obtained by crushing, grinding, or comminuting.

Properly prepared, powders have a uniform, small particle size (varying 10nm-1000μm) that has an elegant appearance. In general, powders are more stable than liquid dosage forms and are rapidly soluble, enabling the drug to be absorbed quickly.

Powders can be broadly classified by the way they are presented/dispensed to the user into bulk powders and divided powders. Other classifications of powders are based on particle size and based on use.

Bulk powders are dry, free-flowing preparations consisting of one or a mixture of finely powdered substances and intended for internal application (e.g., bulk powders for internal use) or external application (e.g., bulk powders for external use). They are supplied in bulk or large quantities and are used for less potent drugs.

Divided powders, or chartulae, are powders in which the individual dose has been packed separately. The traditional packing of divided powders is in wrapped paper. Volatile or hygroscopic drugs are wrapped in aluminium foil or plastic bags.

You will get below benefits from pharmaceutical powders as below:

  1. There is a wide choice of ingredients, and the dose can easily be achieved for patient administration.
  2. Powders have better physicochemical stability and longer shelf life compared to liquid dosage forms. For example, the shelf life of powders for antibiotic syrups is 2 to 3 years, but once reconstituted with water it is 1 to 2 weeks.
  3. Children and adults who have trouble swallowing tablets or capsules may find powders more acceptable.
  4. A large dose that cannot be administered in other forms can be administered as powder. For example, if the dose of a drug is 1 to 5 g it is sometimes not feasible to manufacture tablets to supply the drug to the patient.
  5. A rapid dispersion of drugs occurs in the stomach when given in powder forms rather than in compressed form.
  6. Dissolution rate of oral powders containing water-soluble drugs is generally faster than tablets or capsules, in which disintegration of the tablet or the capsule shell is required prior to dissolution. 7. A powder can be dispersed in water or another liquid and more easily swallowed.
  7. Oral powders can be mixed with beverage or applesauce immediately before use.
  8. Manufacturing of powder dosage form is economic, hence, product cost is quite economic as compared to other dosage forms.
  9. Powders offer a lot of flexibility in compounding solids.

There are some disadvantages of pharmaceutical powders as below:

  1. Powders are not the dosage form of choice for drugs with unpleasant taste. This is because masking of unpleasant tastes may be a problem with this type of preparation.
  2. Drugs that deteriorate rapidly with exposure to atmosphere or acidic pH should not be dispensed as powders. For example, ferrous iron salts are easily oxidized and should not be administered as powders.
  3. Powders are bulky and inconvenient to carry.
  4. Powders are not a suitable dosage form for the administration of drugs that are inactivated in the stomach or drugs which can cause damage to the stomach.
  5. Dispensing potent drugs requiring low doses as powders (e.g., bulk powders) may not be appropriate. This is because individual doses are usually extracted from the bulk using a 5 ml spoon, which is subject to variation in spoon fill (e.g., level or heaped spoonfuls).
  6. Powders are not well suited for dispensing hygroscopic or deliquescent drugs.

Granulation is the process of preparing granules, or physical aggre-gates of powders, in which the original particles can still be identified. Granulation commonly involves adhesion of multiple particles of more than one type of powders. This may be achieved with or without the use of water or naturally adhesive hydrophilic polymers, known as binders. Accordingly, granulation is classified based on the means of achieving the adhesion of its powder components into dry granulation or wet granulation.

Aipak offer two kinds of granulation machine for the processing of powders:

Dry granulation involves compaction of a powder under compressive force of stainless steel rolls, followed by breaking of the compacts into granules of a desired size range. It does not involve any addition of water. The characteristics of the powder particles, such as adhesion, cohesion, fragility, and plasticity, determine the compactibility of a powder.

Wet granulation involves the addition of water, and a binder, to a powder, followed by mixing and removal of water. The binder that becomes well mixed and forms interparticle bonds during granula-tion maintains granules as loosely adhered powder masses even after drying and removal of water.

Helpful Resources For Powder

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Powder Filling Machine:The Complete Buying Guide in 2021

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This is Why you Should Choose Powder Filling Machine: A Buying Guide in 2021

Wet Granulation Machine

Wet Granulation Machine:The Complete Buying Guide in 2021

Interested In Purchasing Your First Powder Machines?

We have helpful resources to help answer common questions about powder machines, the most popular machines, and a helpful guidebook for first-time buyers.

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