What Empty Capsule is Right for You?

1.Selecting Empty Capsules

Selecting of appropriate empty capsule determines the end quality of your formulation. Before making a hasty decision, you need to assess the capacity requirement:

• ARE YOU RUNNING A LARGE-SCALE PRODUCTION?

For this, empty capsules are ideal because in a very shorter time you can meet production demand. Commercially, pharmaceuticals, nutraceutical, veterinary, and herbal industry comes in this category.

• DO YOU REQUIRE AN EMPTY CAPSULE FOR SMALL-SCALE PRODUCTION?

Every small production line, newbie, or hobbyist must avoid selecting an empty capsule without a proper workout. You need to monitor the types, size, and capacity before final selection. Still confused? You can contact a supplier or consult the vendor to guide buying parameters.

• DO YOU NEED EMPTY CAPSULES FOR RESEARCH STUDIES?

For research studies, clinical trials and testing of a new compound in tablet formulation take a longer time. An empty capsule is the best option with few steps procedure for assessment phase I and II clinical studies rather than formulating in other option.

2.Empty Capsules Near Me

After selecting the capsule type; the next task is to find reliable sources. The easiest way is to type “empty capsule near me” in the search engine. Selecting the right manufacturer with positive reviews will guarantee you superior quality products. This search will result in empty capsule suppliers present near your vicinity, such as:

• Amazon
• Alibaba
• eBay

You can also select the top empty capsule manufacturers with the highest market value such as:

• Capsugel (USA)
• Qualicaps (USA)
• Aipak Pharmaceutical (China)
• CapsCanada Corporation (Canada)
• Roxlor LLC (USA)

3.Big or Small Formulation Volume?

When you are in the business of filling capsules, the important question is what will be your formulation volume. Before choosing your required size, it is imperative that you should select your formulation liquid. Capsules can carry out 0.13-1.37 volume of drug.

If you have a larger dose, then you should select a bigger capsule such as‘000 the’ or ‘00’ capsule. If you intend to make a small dose capsule, then go for a 4 or 5-sized capsule.

Here is how should you calculate your preferred size that will encapsulate your required formulation volume.

First, calculate the weight and formulation density.

• Weight is determined by the amount of formulation in milligrams present in each prescribed dose.
• Formulation density is calculated as:
  Density = Mass (g) /Volume (ml)

Look for formulation density that is closer to your actual value (0.8g/ml) so if you have an 800 mg dosage weight then you should select a capsule of 00E.

4.Technique To Fill Capsule

Discussed below are the following capsule filling techniques:

5.How to Fill an Empty Capsule For Oily Formulation?

Previously empty hard gelatin was used for filling powders, pellets, mini-tablets and soft gelatin capsules to encapsulate liquid or semi-solid fills. In the 1980s liquid, hard gelatin capsules were introduced.

With the innovation in technology, presently, empty capsules are easily filled with oily formulations using liquid capsules fillers. These liquid fillers have adjustable nozzles in diameters of 1, 1.5, and 2 mm that are used to fill 0.15 mg up to 1000 mg of liquid by volumetric filling. These can fill up to 60,000-70,000 capsules per hour.

Size and volumes processed by liquid fillers are discussed in the table:

The equipment seal capsules using two methods:

• Hydro-alcoholic fusion method in which <50 ml of sealing solution is applied to cap and body interface and after that warm air is directed to cap-body lock area for sealing solution evaporation.
• The second method includes banding of the cap-body lock area with a thin layer of gelatin.

6.What Type of Capsule Is Best For You? Gelatin Or Vegetarian Capsule

Presently, most people are using empty gelatin capsules as a vehicle for encapsulating their formulation since these are available at a fairly low price. Regardless of price issues vegetarian capsule is a far better option because of the following reasons:

What’s your Choice?

It is up to you to decide which type whether gelatin or vegetarian will you prefer. If you do not have any religious issues or dietary limitations then go for gelatin one because these have low cost. But if you are looking for stability and have a preference for plant-based materials then opt for vegetarian capsules.

7.Key Considerations in Procurement Empty Capsule

The procurement of an empty capsule is a challenging task. For this, we have discussed some points for your assistance:

• Size
  Before purchase, the size of the empty capsule is essential to determine. Because by this way, you can save your time and money.
• Compatibility of Fill Material with Shell
  Understanding the compatibility of your active ingredients with the shell is vital in choosing the right kind of empty capsule for your production. Some protein formulations cause cross-linking of gelatin shell that affects capsule dissolution.
• Reliable Manufacturer
  It is an important step as a trustworthy supplier with the best reviews guarantees superior quality capsules.
• Product Specification
  Be smart and visit your preferred manufacturer’s web page to know about their capsule features such as size, color, shell material, and closure reliability. Besides this, you can contact them personally via email or call for learning about the details of their products.
• Certification
  Check supplier quality certification as GMP, Halal, Kosher, and GMO-free before purchase. These certifications are integral in acceptance by the customers and your product sales.
• Quotation
  Price is one of the important factors when buying empty capsules. After deciding on the right capsule, you can ask the supplier for a product quotation.
• Shipment
  If you are planning to import empty capsules from overseas, after ordering, decide on a delivery method. You can ship your products by air or sea depending upon your required date of delivery. If you urgently need your shipment, then simply dispatch it by air.

CONCLUSION

What Empty Capsule is Right for You? We hope you’ve learned what you look for. Before purchasing an empty capsule, you must go through your market goals as each capsule has its own benefits and drawbacks. If You Are Looking For Free Consultation? or Want To Purchase Empty Capsule Online? Send us a short message to Avail our Support Program.